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Constitutively activated β-catenin signaling, due to APC deficiency or β-catenin mutations that prevent its degradation, leads to excessive stem cell renewal/proliferation that predisposes cells to tumorigenesis

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HCG and relaxin concentrations in early ectopic and normal pregnancies [PMID: 1691474] Laboratory literature summary: hCG and relaxin concentrations in early ectopic and normal pregnancies